Cephradine

CAS number:38821-53-3

Molecular formula:C16H19N3O4S

molecular weight:349.4048

Chemical structure:

Product Name
Cefradine
Shelf Life
2 years
Tests
 BP2012 Specifications Results
Appearance
White or slightly yellow powder,hygroscopic powder.

White powder,

hygroscopic powder.
Solubility Slightly soluble in water,practically insoluble in ethanol 96 percent and in hexane. Conform
Identification IR spectrum should match with that of standard Conform
Clarity of solution Solution S is not more opalescent than reference suspension II
Conform
Absorbance at 450nm Not more than 0.6 0.3
pH
Between 3.0 and 6.0 4.7
Specific optical rotation Between +80.0°and +90.0°(anhydrous substance) +85°
Related substances

Impurity B Maximum0.25% <0.25%
Impurities A, C, D, E, F, G Maximum0.25% <0.25%
Any other impurity Maximum0.5% <0.5%
Total impurity Maximum2.0% <2.0%
N,N-Dimethylaniline
Maximum 20 ppm Not used in process
Water
Maximum 6.0%,determined on 0.300 g. 4.3%
Sulphated ash Maximum 0.2% <0.1%
Assay

cefradine Minimum 90.0% 96.8%
cefalexin Maximum 5.0% 1.5%
4′,5′-dihydrocefradine Maximum 2.0 % 1.0%
Sum of cefradine, cefalexin and 4′,5′-dihydrocefradine Minimum 96.0%.and maximum 102.0%(anhydrous substance) 99.3%