Betamethasone

CAS number:378-44-9

Molecular formula:C22H29FO5

molecular weight:392.46100

Chemical structure:

Product Name BETAMETHASONE BASE
Shelf life 3 years
ITEM SPECIFICATION RESULT
CHARACTER  WHITE OR ALMOST WHITE CRYSTALLINE POWDER  ALMOST WHITE CRYSTALLINE POWDER
SPECIFIC ROTATION +118° TO +126°  +123.6°
IDENTIFICATION (1)COMPLIES BY IR CONFORMS
(2)COMPLIES BY TLC CONFORMS
CHROMATOGRAPHIC PURITY PRINCIPAL IMPURITY NOT MORE THAN 1.0% 0.34%
TOTAL IMPURITIES NOT MORE THAN 2.0% 0.43%
LOSS ON DRYING  NOT MORE THAN 0.5% 0.09%
RESIDUE ON IGNITION NOT MORE THAN 0.2% 0.07%
PARTICLE SIZE (VOLUME METHOD) IT SHOULD BE 90% BELOW 20μm 7.19μm
ASSAY CONTAINS 97.0% TO 103.0% OF C22H29FO3 CALCULATED ON DRIED BASIS 99.2%
CONCLUSION THE PRODUCT CONFORMS TO EP8.0